Fellow Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
Background: Non-English language preference (NELP) has been associated with poorer health outcomes in children, thus further understanding how it affects care is imperative. NELP has been associated with worse health care access and quality, adverse events, sepsis mortality, and increased lengths of stay. Although NELP is known to lead to worsened outcomes in children, there have not been studies directly examining NELP in CKD progression and pediatric renal transplant outcomes. Objective: This study will characterize how NELP is affecting the CKD progression and the renal transplant process for children. This will promote more equitable care and outcomes. Design/Methods: This single-center retrospective cohort study was approved by the Institutional Review Board at New York Medical College. Information about patient demographics, BMI, blood type, renal function, primary causes of ESRD, CKD measures and medications, and transplant outcomes will be collected from a cohort of children aged < 21 years who received kidney transplants Jan 2004 - Sept 2022. We will use descriptive statistics for patient demographics and clinical variables of interest; the Wilcoxon rank sum test and t-test for continuous variables; and Chi-squared and Fisher's exact for categorical variables. Our preliminary data showed that 26% of the 45 patients included in the study were identified as NELP. The average age at transplant for NELP and ELP patients was 12.3 (± 5.3) and 10.7 (± 5.4) years, respectively. NELP showed a worsened estimated glomerular filtration rate on average, with serum creatinine of 7.43 compared to ELP at 5.91 at time of transplant. Data will continue to be collected to explore the progression of renal failure in this patient cohort with the measures described above. A complete analysis will include the pre-transplant trajectory and post-transplant trajectory.
