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Evaluation ViewAttendees 73
Debate/Pro-Con Discussion

General Pediatrics

Hospital Medicine

Infectious Diseases

Neonatology

Pharmacology and Therapeutics

Public Health

Well Newborn
Session Type: Debate/Pro-Con Discussion

Congenital Syphilis and Neonatal Herpes: The Debate is On!

Monday, May 6, 2024
8:00 AM – 9:30 AM ET
Location: Metro Toronto Convention Centre: 205
CE: Live CME: 1.5

Selected By: PIDS
Co-sponsored By: Neonatal

    Chair(s)

  • Pablo Sanchez, MD

    Professor of Pediatrics
    Pediatrics
    Nationwide Children's Hospital -OSU
    Columbus, Ohio, United States

Disclosure(s):
Pablo J. Sanchez, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Session

Description: This session involves as PRO/CON debate on 2 topics:
1) Congenital syphilis: benzathine penicillin is OK for the normal Infant
2) Neonatal herpes simplex virus (HSV) infection: asymptomatic newborns of mothers with active genital herpes infection: is a lumbar puncture and acyclovir needed? (Speakers David Kimberlin and "To be Announced")
Both of these topics are much discussed in clinical practice. The use of benzathine penicillin for infants born to mothers with untreated or inadequately treated syphilis and when the infant evaluation is normal has a long history of effectiveness, yet this therapy is not frequently utilized as many clinicians treat for 10 days of intravenous penicillin therapy. This results in mother-infant separation, NICU admission, and prolonged hospital stay. With respect to the newborn exposed to active "primary" maternal genital HSV lesions, the recommendation has been to evaluate the infant fully, including a lumbar puncture. Even when the evaluation is negative, a prolonged course of acyclovir is recommended, which means NICU admission, maternal-infant separation, and increased hospital costs. Bothof these topics will be debated ina PRO/CON manner.

Learning Objectives:

  • To know when benzathine penicillin can be sued safely in the newborn exposed to maternal syphilis
  • To know when a lumbar puncture is indicated in a newborn exposed ot active maternal genital HSV lesions
  • To understand the potential adverse effects of our medical management

Presentations:

  • 8:00 AM – 8:15 AM ET
    Benzathine penicillin is OK for the normal newborn exposed to untreated maternal syphilis

    Speaker: Pablo J. Sanchez, MD – Nationwide Children's Hospital -OSU

  • 8:15 AM – 8:30 AM ET
    Benzathine penicillin is NOT OK for the normal newborn exposed to untreated maternal syphilis

    Speaker: Ryan Rochat, MD, PhD, MS (he/him/his) – Baylor College of Medicine and Texas Children's Hospital