Neonatal Neurology 3: Preclinical

Moderator(s)

• 

  Camille Fung, MD (she/her/hers)

  Associate Professor
  Pediatric Neonatology
  University of Utah
  Salt Lake City, Utah, United States
• 

  Anna Penn, MD PhD (she/her/hers)

  L. Stanley James Associate Professor of Pediatrics & Chief, Division of Neonatology
  Columbia University Vagelos College of Physicians and Surgeons
  New York, New York, United States

Presentations:

• 2:00 PM – 2:15 PM ET

  Glutamate receptor (GluR) agonist, 2-chloro-5-hydroxyphenylglycine (CHPG), preserves primary myelination disrupted by intermittent hypoxia in neonatal mice.
  

  Presenting Author: Casey E. Lamar, MD (he/him/his) – Rutgers, Robert Wood Johnson Medical School
• 2:15 PM – 2:30 PM ET

  D-Syn3 Reduced Brain Volume Loss and Affected p-Tau Expression in Neonatal Rats with Exposure to Hypoxic-Ischemic Brain Injury
  

  Presenting Author: Xiaodi Felix Chen, MD, PhD (he/him/his) – Women & Infants Hospital of Rhode Island
• 2:30 PM – 2:45 PM ET

  Human ApoE4 haplotype impairs bioenergetic responses to neonatal hypoxia-ischemia and increases neuroinflammation in mice.
  

  Presenting Author: Raul Chavez-Valdez, MD (he/him/his) – Johns Hopkins University School of Medicine
• 2:45 PM – 3:00 PM ET

  Neuroimmune organoids: a model to study role of microglia in human neurodevelopment in physiologic and pathologic conditions.
  

  Presenting Author: Samhita Jain, MD (she/her/hers) – University of California, San Francisco
• 3:00 PM – 3:15 PM ET

  Intranasal human umbilical Mesenchymal Stromal Cells Augment Therapeutic Hypothermia in a Piglet Hypoxia-Ischemia Model
  

  Presenting Author: Alison Mintoft, MBChB – University College London
• 3:15 PM – 3:30 PM ET

  Efficacy of Cytoprotective Therapies in Newborn Piglets following Inflammation-Amplified Hypoxia-Ischaemia: a Large Multidrug Preclinical Trial
  

  Presenting Author: Raymand Pang, MB ChB, PhD – University College London