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Evaluation ViewAttendees 48
Hot Topic Symposia

Children with Chronic Conditions

General Pediatrics

Hematology/Oncology

Hospital Medicine

Nephrology
Session Type: Hot Topic Symposia

New insights into the development and progression of kidney disease in sickle cell disease

Friday, May 3, 2024
5:15 PM – 6:45 PM ET
Location: Metro Toronto Convention Centre: 801 B
CE: Live CME: 1.5

Selected By: ASPN
Disclosure(s):
Stefanie W. Benoit, MD, MPH: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Sushil Gupta, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Session

Description: Sickle cell disease is a multi-organ disease that may impact short and long term kidney function by a variety of mechanisms. Recent studies have provided important insights into the pathogenesis of sickle cell-associated kidney disease, including defining the role of specific genetic, immunologic and biochemical risk factors for development and progression of kidney disease. Identifying early stage kidney disease and defining the optimal timing and type of intervention remain challenging.
The overall goal of this session is to provide the audience with an understanding of the pathophysiology of kidney involvement in sickle cell disease (and sickle trait), the factors that contribute to development of kidney disease progression, biomarkers for acute and chronic kidney disease, and management and outcome of end stage kidney disease.

Learning Objectives:

  • Define the mechanisms by which sickle cell disease and sickle cell trait can affect the kidney and the complications that can result.
  • Delineate risk factors for progression of sickle cell nephropathy and the effects of stem cell transplantation on CKD in sickle cell disease.
  • Delineate the issues that may arise in management of ESKD in patients with sickle cell disease and outcomes of dialysis and transplant in this population.

Presentations:

  • 5:15 PM – 5:40 PM ET
    Pathophysiology of kidney disease in sickle cell disease and sickle cell trait

    Speaker: Kenneth I. Ataga, MD – UTHSC at Memphis

  • 5:40 PM – 6:05 PM ET
    Can we prevent sickle cell nephropathy? The role of modifiable and non-modifiable factors in kidney disease progression

    Speaker: Daniel I. Feig, MD/PhD (he/him/his) – University of Alabama, Birmingham, Heersink School of Medicine

  • 6:05 PM – 6:30 PM ET
    Dialysis and transplantation in sickle cell disease: Specific considerations and outcomes of ESKD

    Speaker: Rima Zahr, DO (she/her/hers) – University of Tennessee Health Science Center College of Medicine