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Evaluation ViewAttendees 180
Panel Discussion

Clinical Research

Neonatology

Pharmacology and Therapeutics

Trainee
Session Type: Panel Discussion

Systemic Corticosteroid Use in Neonates: Contemporary Controversies and Current Evidence

Saturday, May 4, 2024
8:00 AM – 9:30 AM ET
Location: Metro Toronto Convention Centre: 105
CE: Live CME: 1.5

Selected By: Neonatal
Disclosure(s):
Kristi L. Watterberg, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Andrea F. Duncan, MD. MSCR: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Session

Description: Despite decades of research, controversy about the optimal use of systemic corticosteroids in neonates remains. Recent trends suggest growing use of hydrocortisone (HCTZ) among preterm infants. However, somewhat conflicting results on the short and longer-term benefits of HCTZ
has led to uncertainty regarding patient selection and optimal timing for initiation. While recent well-designed multi-center, randomized controlled trials on HCTZ have been informative, fundamental questions on safety and effectiveness remain unanswered. Moreover, renewed interest in the potential value of dexamethasone as an alternative to HCTZ warrants careful consideration. At present, healthcare professionals lack equity-focused, evidence-based data to guide their clinical management.

Learning Objectives:

  • Describe regional and national hospital variation in systemic corticosteroid use among preterm infants.
  • Determine the strengths and limitations of evidence for systemic corticosteroid use among preterm infants.
  • Discuss the need for clinical equipoise regarding treatment options, highlighting the value of pragmatic clinical trials to inform the practice of equity-focused, evidence-based medicine.

Presentations:

  • 8:00 AM – 8:05 AM ET
    Systemic Corticosteroid Use: Contemporary Controversies and Questions

    Speaker: Ashley C. Wethall, MD (she/her/hers) – Nationwide Children's Hospital

  • 8:05 AM – 8:20 AM ET
    Early Uses of Hydrocortisone Among Preterm Infants

    Speaker: olivier baud, MD PhD (he/him/his) – Hopitaux universitaires de Genève

  • 8:20 AM – 8:35 AM ET
    Systemic Corticosteroid Use on Chronic Lung Disease

    Speaker: Erik A. Jensen, MD, MSCE (he/him/his) – Children's Hospital of Philadelphia

  • 8:35 AM – 8:50 AM ET
    Systemic Corticosteroids on Longer-term Patient Outcomes

    Speaker: Jean R. Lowe, PhD (she/her/hers) – University of New Mexico School of Medicine

  • 8:50 AM – 9:05 AM ET
    Dexamethasone to Prevent Chronic Lung Disease

    Speaker: Lex W. Doyle, MB, BS, MD, MSc – Prof. Lex Doyle

  • 9:05 AM – 9:20 AM ET
    Systemic Corticosteroid Use in Neonates: What Have We Learned and Where Should We Go Next?

    Speaker: Kristi L. Watterberg, MD (she/her/hers) – University of New Mexico School of Medicine