Clinical Post-Doctoral Fellow Texas Children's Hospital | Baylor College of Medicine HOUSTON, Texas, United States
Background: A predominant mother’s-own-milk (MOM) diet in very low birth weight (VLBW; =1500 grams) infants reduces morbidity and mortality of prematurity-related diseases. Colostrum as oral care (oral immune therapy; OIT), promotes an anti-inflammatory environment in the premature gut. Pump-dependent mothers of VLBW infants rely on frequent and effective pumping, especially during the first 14 postnatal days, to establish an adequate milk supply. Hospital-grade breast pumps, available for free in our neonatal intensive care unit (NICU), aid in mother’s milk production. However, accessing these pumps for home use can be financially challenging. Objective: This study examined differences in MOM and OIT intake in VLBW infants in the first 28 days of life following implementation of a bundle providing breastfeeding education, support for pump-dependent mothers, and a free 1-month hospital-grade breast pump rental. Design/Methods: The study was approved by the institution’s review board. Power analysis indicated that 50 pre- and post-intervention patients would provide 80% power to detect a mean MOM increase from 62.9% to 85.7%. The retrospective group included VLBW infants born consecutively at a quaternary academic NICU from September to December 2022. Prospective enrollment with informed verbal consent has been ongoing since January 2023. Exclusion criteria included death or discharge prior to 28 postnatal days, mothers unable or unwilling to provide MOM, congenital anomalies, and chromosome defects excluding Trisomy 21. Data collection included maternal and neonatal demographics, socioeconomic factors, prematurity-related comorbidities, and enteral nutrition information focusing on MOM and OIT percentages in the first 28 days of life. Data will be summarized using descriptive statistics and compared between the two groups. As of October 2023, 88 prospective patients were enrolled with 38 excluded, 12 pending data collection, and 38 with preliminary data. Retrospective data collection is complete. Enrollment and data analysis are anticipated to conclude by January 2024.